Year : 2015  |  Volume : 2  |  Issue : 2  |  Page : 55-59

Anti-thrombotic Regime for Percutaneous Intervention in Peripheral Arterial Disease: A Need of the Hour

1 Department of Pharmacology, M.S. Ramaiah Medical College, Bengaluru, Karnataka, India
2 Department of Vascular Surgery, M.S. Ramaiah Medical College, Bengaluru, Karnataka, India

Correspondence Address:
Dr. Pallavi Kawatra
Department of Pharmacology, M.S. Ramaiah Medical College, Bengaluru, Karnataka
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0972-0820.161942

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Peripheral arterial disease, a significant contributor to morbidity and mortality, is an imperative marker of a coexisting subclinical coronary artery disease. Since most of the patients become symptomatic at a later stage, a surgical approach becomes inevitable in these patients. With the introduction of percutaneous transluminal angioplasty, it has been possible to preclude numerous amputations. However, this procedure comes with the drawback of restenosis on the long term. In order to overcome this problem, a plethora of inconsistent regimes, pertaining to anti-thrombotics are being prescribed. In the face of the current scenario, to overcome the preordained outcome of restenosis, this systematic review highlights the problem of restenosis experienced in daily practice. It also discusses some commonly used anti-thrombotics and their success in various clinical trials suggesting the absolute need of a protocol for prescribing these drugs before and after angioplasty.

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