Chronic kidney disease and anticoagulation - Quick overview and practical guide

Pranay Purushotam Pawar; Albert Abhinay Kota; Indrani Sen; Edwin Stephen; Bader Al Rawahi; Santosh Varughese; Saif Khan

doi:10.4103/ijves.ijves_90_21

Users Online: 108

ORIGINAL ARTICLE

Year : 2022 | Volume : 9 | Issue : 1 | Page : 40-47

Chronic kidney disease and anticoagulation - Quick overview and practical guide

Pranay Purushotam Pawar¹, Albert Abhinay Kota², Indrani Sen³, Edwin Stephen⁴, Bader Al Rawahi⁵, Santosh Varughese⁶, Saif Khan⁷
¹ Vascular Surgery Unit, Department of Surgery, Christian Medical College and Hospital, Ludhiana, Punjab, India
² Department of Vascular Surgery, Christian Medical College, Vellore, Tamil Nadu, India
³ Department of Vascular Surgery, Mayo Clinic, Rochester, Minnesota, USA
⁴ Department of Vascular Surgery, Sultan Qaboos University Hospital, Muscat, Oman
⁵ Department of Hematology, Sultan Qaboos University Hospital, Muscat, Oman
⁶ Department of Nephrology, Christian Medical College, Vellore, Tamil Nadu, India
⁷ Department of Nephrology, Sultan Qaboos University Hospital, Muscat, Oman

Correspondence Address:
Edwin Stephen
Department of Vascular Surgery, Sultan Qaboos University Hospital, Muscat
Oman

Source of Support: None, Conflict of Interest: None

Check

DOI: 10.4103/ijves.ijves_90_21

Clinicians managing patients with chronic/end-stage renal disease often are challenged when it comes to anticoagulation in this subset. Unfractioned heparin and warfarin have been in use, and most multidisciplinary teams are comfortable with the drug/s either as prophylaxis or for full anticoagulation. Over the past decade, there has been an increase in the use of low-molecular-weight heparin and more recently of direct oral anticoagulants for anticoagulation. However, there is a reluctance to use these drugs for concern of increased bleeding and management of this complication in patients with renal disease. This paper shares a quick overview of coagulation in chronic/end-stage kidney disease and drugs used for anticoagulation, societal recommendations for their use, with clinical case scenarios, and a proposed management algorithm when patients have a bleed while on anticoagulation.

[FULL TEXT] [PDF]*

Table of Contents

Similar in PUBMED

Search Pubmed for

Search in Google Scholar for

Related articles

Citation Manager

Access Statistics

Reader Comments

Email Alert *

Add to My List *

* Requires registration (Free)

Article Access Statistics

Viewed	350

Printed	6

Emailed	0

PDF Downloaded	28

Comments	[Add]